![]() Theriac in the Persian traditional medicine. Taghizadieh A., Mohammadinasab R., Sharbaf J.G., Michaleas S.N., Vrachatis D., Karamanou M. The dose response principle from philosophy to modern toxicology: the impact of ancient philosophy and medicine in modern toxicology science. Tsatsakis A.M., Vassilopoulou L., Kovatsi L., Tsitsimpikou C., Karamanou M., Leon G., Liesivuori J., Hayes A.W., Spandidos D.A. Submitted by Robert Adam Leigh to the University of Exeter as a thesis for the degree of Doctor of Philosophy in Classics in July 2013. This is mainly attributed to it is possible risks, uncertainty about its benefits 25 28, and that clinicians have less interest in GI decontamination as a mode of therapy. Galen, On Theriac to Piso, A critical edition with translation and commentary. AC is still considered a universal antidote for acutely poisoned patients, eventhough its use has declined significantly in recent years. ![]() Colchis – Iberian medicine or Cura Mediana. It contains an analysis of historical toxicological treatises on antidotes and PubMed articles on the same topic.Īntidote Experimental toxicology Poisoning Specific antidote Universal antidote. This review article focuses on the changing conceptualization of antidotes. A phase 2 randomized, double-blind, placebo-controlled trial of PRT064445, a novel, universal antidote for direct and indirect factor Xa inhibitors. Among the theories of antidote, the most interesting is the concept of a universal one, because it has never become obsolete. From this perspective, the history of antidotes may be considered as the quintessence of changes within toxicology. The concept of antidote was changing in line with the progress of medicine and understanding of the mechanism of how poison works. With the passing of time, different substances of plant, animal, and mineral origin, moreover, man-made ones, were used deliberatively, accidentally, or unintentionally as poisons. Over the centuries, the development of knowledge about poisons and antidotes depended on their conceptualization, however, a range of poisons and the concept of antidote evolved.
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